Gaetano Lombardi Selected Research

Octreotide (Sandostatin)

4/2011	Resistance to somatostatin analogs in acromegaly.
10/2009	Effects of initial therapy for five years with somatostatin analogs for acromegaly on growth hormone and insulin-like growth factor-I levels, tumor shrinkage, and cardiovascular disease: a prospective study.
11/2008	Effect of treatment with depot somatostatin analogue octreotide on primary hyperparathyroidism (PHP) in multiple endocrine neoplasia type 1 (MEN1) patients.
9/2008	Growth hormone-secreting tumor shrinkage after 3 months of octreotide-long-acting release therapy predicts the response at 12 months.
11/2007	Beneficial effect of dose escalation of octreotide-LAR as first-line therapy in patients with acromegaly.
5/2007	SOM230, a new somatostatin analogue, is highly effective in the therapy of growth hormone/prolactin-secreting pituitary adenomas.
6/2006	Predictors of tumor shrinkage after primary therapy with somatostatin analogs in acromegaly: a prospective study in 99 patients.
3/2006	Efficacy of 12-month treatment with the GH receptor antagonist pegvisomant in patients with acromegaly resistant to long-term, high-dose somatostatin analog treatment: effect on IGF-I levels, tumor mass, hypertension and glucose tolerance.
3/2006	First-line octreotide-LAR therapy induces tumour shrinkage and controls hormone excess in patients with acromegaly: results from an open, prospective, multicentre trial.
1/2006	Partial surgical removal of growth hormone-secreting pituitary tumors enhances the response to somatostatin analogs in acromegaly.

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Gaetano Lombardi Research Topics

Disease

33	Acromegaly 09/2013 - 03/2002
33	Neoplasms (Cancer) 07/2011 - 02/2003
22	Insulin Resistance 11/2011 - 06/2003
18	Pituitary Neoplasms (Pituitary Adenoma) 12/2018 - 06/2002
16	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 07/2009 - 02/2003
15	Prolactinoma (Prolactinomas) 07/2011 - 06/2002
14	Adenoma (Adenomas) 07/2011 - 06/2002
11	Hyperprolactinemia 09/2007 - 06/2002
9	Cushing Syndrome 01/2010 - 11/2002
9	Cardiovascular Diseases (Cardiovascular Disease) 10/2009 - 01/2004
8	Hypertension (High Blood Pressure) 11/2011 - 11/2002
7	Osteoporosis 08/2022 - 04/2002
7	Leiomyoma (Uterine Fibroids) 07/2005 - 08/2002
6	Cardiomyopathies (Cardiomyopathy) 11/2011 - 07/2002
6	Hyperthyroidism 03/2009 - 03/2002
6	Pituitary ACTH Hypersecretion 01/2009 - 03/2003
6	Atherosclerosis 12/2008 - 03/2002
6	Hypothyroidism 03/2007 - 12/2002
5	Obesity 08/2011 - 05/2003
4	Carcinogenesis 04/2012 - 10/2006
4	Neuroendocrine Tumors (Neuroendocrine Tumor) 03/2012 - 01/2007
4	Glucose Intolerance 11/2011 - 11/2002
4	Diabetes Mellitus 01/2010 - 05/2003
4	Thyroid Neoplasms (Thyroid Cancer) 01/2009 - 01/2003
3	COVID-19 03/2022 - 01/2020
3	Body Weight (Weight, Body) 06/2015 - 02/2003
3	Inflammation (Inflammations) 08/2011 - 04/2005
3	Carcinoma (Carcinomatosis) 01/2010 - 09/2004
3	Hypogonadism (Hypergonadotropic Hypogonadism) 09/2005 - 02/2003
3	Hypopituitarism (Sheehan's Syndrome) 12/2004 - 04/2004
3	Hypertrophy 06/2004 - 01/2003
2	Metabolic Bone Diseases (Osteopenia) 08/2022 - 02/2005
2	Apnea 03/2022 - 02/2004
2	Postoperative Pain 01/2019 - 01/2019
2	Overweight 08/2011 - 10/2004
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2010 - 06/2003
2	Hyperandrogenism 07/2009 - 10/2008
2	Thyroid Nodule (Nodule, Thyroid) 03/2009 - 10/2003
2	Hypercalciuria 11/2008 - 05/2003
2	Parkinson Disease (Parkinson's Disease) 10/2008 - 04/2005
2	Adenocarcinoma 10/2007 - 08/2007

Drug/Important Bio-Agent (IBA)

28	Insulin-Like Growth Factor I (IGF-1)IBA 08/2011 - 03/2002
19	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 09/2013 - 02/2003
19	Growth Hormone (Somatotropin)IBA 08/2011 - 04/2003
18	Glucose (Dextrose)FDA LinkGeneric 11/2011 - 02/2004
18	Cabergoline FDA LinkGeneric 01/2009 - 06/2002
15	LipidsIBA 11/2011 - 11/2002
14	ProlactinIBA 04/2012 - 06/2002
14	Octreotide (Sandostatin)FDA LinkGeneric 04/2011 - 01/2003
12	Insulin (Novolin)FDA Link 11/2011 - 03/2002
10	Dopamine Agonists (Dopamine Agonist)IBA 07/2011 - 06/2002
10	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2008 - 11/2002
9	lanreotide (Somatuline)FDA Link 04/2011 - 03/2002
7	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2010 - 04/2004
7	Testosterone (Sustanon)FDA Link 10/2008 - 01/2003
7	Raloxifene Hydrochloride (Evista)FDA Link 07/2005 - 08/2002
6	TabletsIBA 01/2019 - 04/2002
6	Hormones (Hormone)IBA 02/2010 - 06/2002
6	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2009 - 01/2003
6	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2009 - 12/2002
6	Dopamine Receptors (Dopamine Receptor)IBA 12/2008 - 04/2004
6	Gonadotropin-Releasing Hormone (GnRH)FDA Link 04/2005 - 10/2002
5	HDL CholesterolIBA 11/2011 - 08/2004
5	Somatostatin Receptors (Somatostatin Receptor)IBA 04/2011 - 04/2003
5	Thyroid HormonesIBA 01/2009 - 03/2002
5	Leuprolide (Lupron)FDA LinkGeneric 04/2005 - 10/2002
4	Fibrinogen (Factor I)FDA Link 01/2021 - 03/2002
4	C-Reactive ProteinIBA 08/2011 - 07/2006
4	GlucocorticoidsIBA 01/2010 - 04/2005
4	Proteins (Proteins, Gene)FDA Link 03/2009 - 10/2004
4	Pharmaceutical PreparationsIBA 01/2009 - 12/2002
4	Bromocriptine (Parlodel)FDA LinkGeneric 04/2006 - 06/2002
3	HMGA ProteinsIBA 12/2018 - 03/2009
3	Triglycerides (Triacylglycerol)IBA 11/2011 - 09/2008
3	Arginine (L-Arginine)FDA Link 05/2011 - 04/2005
3	CytokinesIBA 12/2007 - 04/2005
3	Diphosphonates (Bisphosphonates)IBA 12/2007 - 02/2005
3	Metformin (Glucophage)FDA LinkGeneric 07/2007 - 10/2004
3	AntibodiesIBA 06/2007 - 04/2003
3	GonadotropinsIBA 11/2005 - 04/2004
3	AdiponectinIBA 10/2004 - 06/2003
2	antineoplaston A10 (A 10)IBA 01/2021 - 11/2011
2	Sufentanil (Sufenta)FDA LinkGeneric 01/2019 - 01/2019
2	LDL CholesterolIBA 11/2011 - 08/2004
2	Insulin-Like PeptidesIBA 08/2011 - 01/2004
2	Uric Acid (Urate)IBA 08/2011 - 05/2003
2	CholesterolIBA 08/2011 - 08/2004
2	AndrogensIBA 07/2009 - 09/2004
2	Interferon Type IIBA 03/2009 - 08/2007
2	Thyrotropin Alfa FDA LinkGeneric 01/2009 - 01/2003
2	Phosphorus (Red Phosphorus)IBA 11/2008 - 05/2003
2	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2008 - 06/2005
2	Estrogens (Estrogen)FDA Link 10/2008 - 03/2007

Therapy/Procedure

32	Therapeutics 09/2013 - 11/2002
9	Radiotherapy 07/2011 - 06/2002
6	Aftercare (After-Treatment) 08/2009 - 12/2002
5	Drug Therapy (Chemotherapy) 07/2009 - 02/2004
4	Stem Cell Transplantation 12/2006 - 05/2003
2	Mechanical Ventilators (Ventilator) 04/2020 - 01/2020
2	Gynecologic Surgical Procedures (Gynecologic Surgery) 01/2019 - 01/2019